AN UNBIASED VIEW OF MS-444

Furthermore, RNA-FISH and luciferase reporter analyses showed that MS-444 blocked the nucleocytoplasmic transport of Agbl2 mRNA and decreased its stability by inhibiting HuR dimerization. Additionally, optimized stochastic optical reconstruction microscopy (STORM) imaging showed that MS-444 drastically minimized the HuR dimerization, and HuR mainly